The efficacy of magnesium sulfate administration in diffuse axonal injury cases

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The effects of magnesium sulfate therapy after severe diffuse axonal injury

PURPOSE To evaluate the clinical effects of magnesium sulfate in the treatment of diffuse axonal injury (DAI). PATIENTS AND METHODS This study was a randomized, double-blind, placebo-controlled trial conducted in the First Affiliated Hospital of Sun Yat-sen University, Guangzhou and Zhuhai People's Hospital, Zhuhai, two trauma center hospitals. A total of 128 patients suffered from DAI, with ...

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magnesium sulfate effect on the clinical course and gcs of patients with a severe diffuse axonal injury

based on a number of studies, magnesium sulfate (mgso4) given after a diffuse axonal injury has gained attention as a useful neuroprotective agent .the present study was conducted to examine if magnesium sulfate has a therapeutic efficacy and safety in patients with a severe diffuse axonal injury. adult patients admitted within 1 hour of a closed traumatic brain injury (tbi) with a severe diffu...

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Effects of Magnesium Sulfate Administration on Testicular Ischemia/Reperfusion Injury in Rats

This study aimed at investigating the effects of intraperitoneal (IP) administration of magnesium sulfate (MgSO4) on testicular ischemia-reperfusion (IR) injury in rats. In total, 50 adult Wistar rats were randomly divided into 5 groups. Group 1 received no injection (control); however, group 2 was subjected to 2 h of I and 24 h of R. Subsequently, group 3 was subjected to 2 h of 1, ...

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Effects of magnesium sulfate on the clinical course and GCS of patients with a severe diffuse axonal injury

Background: Previous studies have shown that magnesium sulfate (MgSO4) administered in a patient with a diffuse axonal injury (DAI) can serve as a useful neuroprotective agent. The present study was conducted to examine whether magnesium sulfate has a therapeutic efficacy and safety in patients with a severe diffuse axonal injury. Methods: Adult patients admitted within 1 hour of a closed Traum...

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Magnesium offers theoretic vascular and neuroprotective benefits for patients with subarachnoid hemorrhage. An electronic literature search was conducted to identify original research studies describing intravenous magnesium treatment in patients with SAH published in English between January 1990 and October 2010. Seventeen articles were identified and reviewed, including one phase III randomiz...

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ژورنال

عنوان ژورنال: Indonesian Journal of Neurosurgery

سال: 2020

ISSN: 2338-9524

DOI: 10.15562/ijn.v3i1.104